MBB 201 Lecture Notes - Lecture 7: Polysaccharide, Contour Line, Acetyl Group

• School: Simon Fraser University
• Department: Molec Biol & Biochem
• Course: MBB 201
• Professor: Frederic Pio

Document Summary

If folded incorrectly they can damage cells or tissues: folding is usually assisted by chaperone proteins, or may be placed in an isolation chamber so that it can fold without interruption. Bonds: disulphide bonds only form between cysteine and not cytosol because too many reducing agents in cytosol, can form within the same chain, or between two adjacent chains, very strong (help make keratin) Representations of protein conformers: backbone- shows backbone, ribbon- shows backbone and emphasizes secondary structure, wire- shows backbone and side chains, space filling- provides a contour map of the surface. Protein families: each member as an amino acid sequence and a 3d conformation that closely resemble the other members. Protein folding and free energy: all molecules of a given protein species adopt the same 3d conformation despite the countless folding possibilities: native state. Transition state: the maximum energy species formed on the reaction coordinate- a part of the process of the reaction.