MBB 222 Lecture Notes - Lecture 31: Rna Polymerase Iii, Rna Polymerase Ii, Rna Polymerase I

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Eukaryotes have three different rna polymerases (rnaps) for synthesis of different. Rna polymerase i (rnap i) in nucleolus synthesizes rrna part of ribosomes. Rna pol ii (rnap ii) in nucleus synthesizes mrna proteins. Rna pol iii (rnap iii) in nucleus synthesizes trna (adaptor for protein synthesis), 5s. ~80% of the total rna in rapidly growing mammalian cells is rrna and 15% is trna; protein- coding mrna constitutes only a small portion of the total rna but is very diverse. The relationship between an mrna"s nucleotide sequence and protein amino acid sequence. A degenerate code, most amino acids have multiple codons. This table will be provided on the final exam, but be sure you know how to use it. The initiation (or start ) codon aug is at the start of a gene signals the start of protein synthesis. Aug encodes met so a met is inserted as the first amino acid in every protein.

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