PSYC 280 Lecture Notes - Lecture 8: Fluvoxamine, Paroxetine, Antibody

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Depression is the most prevalent mood disorder. Depression: a psychiatric condition characterized by such symptoms as an unhappy mood, loss of interests, energy and appetite, and difficulty concentrating. Unipolar depression: depression that alternates with normal emotional states: can occur with no readily apparent stress. Bipolar disorder or manic depressive illness: characterized by repeated fluctuation between depressive periods and episodes of euphoric, sometimes grandiose, positive mood or mania. Depression is very lethal and suicide is often committed impulsively. Many genes contribute to make a person more or less susceptible. Increase in blood flow, prefrontal cortex and amygdala show greater activity. Blood flow decreases in the parietal and posterior temporal cortex and in the anterior cingulate o. Descendants of people with severe depression also have a thinner cortex across large swaths of the right hemisphere than do control subjects. Transcranial magnetic stimulation is being used for treatment. Most common treatment for depression are antidepressants to affect monoamine transmitters.

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