PSYC 3230H Lecture 2: September 18 Neural Basis of Sleep

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22 Dec 2018
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Lesion studies: watching/observing/recording sleep of those who have lesions, nonhumans (animals, humans. Stimulation studies: stimulating certain parts of the brain and then recording what happens when that brain region is stimulated, ore arousal or more sleep produced, typically done on nonhumans. Recording studies: recording the cellular activity during sleep. Inserting electrodes into the brain: typically done on nonhumans. If a brain region is suspected to be involved with sleep, destroy it, and see what happens. Reticular formation: von economo (1916, encephalitis lethargica (virus) The sleeping sickness central nervous system disorder: killed millions at the time. Immune system began to attack itself would essentially destroy parts of the brain: either showed difficulty falling asleep or difficulty staying awake. Led to the understanding of how sleep is controlled. Damage to anterior midbrain associated with prolonged wakefulness (anterior hypothalamus) Damage to posterior midbrain associated with prolonged sleepiness. Two major pathways (for waking) from aras: thalamic pathway.

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