PSYC 3230H Lecture 4: October 2 Evolution of sleep

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22 Dec 2018
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Two process model of sleep regulation (by borbely 1980: process c circadian process, process s homeostatic process (sleep need/pressure) The longer you"re awake, the more pressure there is to go to sleep. If process c was the only one, we wouldn"t need naps. When you sleep, the homeostatic pressure to sleep goes away. It doesn"t decline until you go to sleep. Adenosine is a metabolite of adenosine triphosphate, a large energy source molecule. Might signal about need to replenish energy. Longer you are awake, the higher the levels get. Adenosine is a neuromodulator (chemical that regulates other chemicals) Adenosine levels build up over the day when we are awake and then decline with sleep. Biproduct of atp (energy storage molecule- helps power our cells) Stimulants like caffeine actually work against the action of adenosine (antagonists). They promote alertness by preventing action of adenosine. They get more slow wave sleep (delta) and more rem after being sleep deprived.

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