BIOL 2000 Lecture Notes - Hydrogen Bond, Ribosome, Protein Structure
Document Summary
Protein synthesis occurs through the process called translation. Translation occurs on rnp particles called ribosomes. Ribosome- large rnp complex: catalyzes peptide bond formation. Transfer rnas- trnas: non coding rnas, bring amino acids to the ribosome, decode information on the mrna. Messenger rnas (mrnas: template for protein synthesis. Protein sequence and 3d shape influences function: molecules can be bound, cellular location, protein-protein interactions. Shape affects type of molecules proteins can bind to and work. Protein 3d structure is stabilized by: with: ionic interactions, hydrogen bonding (h-bonds, hydrophobic interactions and van der waals forces. Each individual bond is weak but add them up and it gives protein their structure. There are 20 different standard amino acids in proteins. Side chain r group is different for each one. Different r group properties: charged (+ or -, hydrophobic, hydrophilic, aromatic. Chain of amino acids are linked by peptide bonds: makes a polypeptide. Always same bond no matter the specific amino acid.
