NEUR 2600 Lecture Notes - California Sea Hare, Eric Kandel, Axon Terminal

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19 Mar 2013
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Calcium = ion, carries 2 charges voltage sensitive channels on neuron terminals. Binds to calmodulin, binds to vesicles releasing some from filaments and inducing others to bind to the presynaptic membrane and to empty their contents. Define: the response to a stimulus weakens with repeated presentation. Given that a particular stimulus elicits a response, repeated applications of the stimulus results in decreased response. If the stimulus is withheld, the response tends to recover over time (spontaneous recover) If repeated serious of habituation training and spontaneous recovery are given, habituation becomes successively more rapid. Other things being equal, the more rapid the frequency of stimulation, the more rapid and/or more pronounced is habituation. The weaker the stimulus, the more rapid and/or more pronounces is habituation. The effects of habituation training may proceed beyond the zero or asymptotic response level. Habituation of response to a given stimulus exhibits stimulus generalization to other stimuli. Gill no longer withdraws from water jet demonstrating habituation.

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