NEUR 2600 Lecture Notes - Tight Junction, Latrodectus, Pineal Gland
Document Summary
Drugs can act as agonists, or antagonists (decreases) 5 classes of drugs based on behavioural effects. There is no one-to-one action of a drug as most have effects at many different kinds of synapses and these diverse effects often account for the side effects of their actions. Injecting a drug directlyi nto the brain allow it to act quickly in low doses because there are no barrier. Take drugs orally is the safest, easiest and more convenient way to administer them. Drugs that are weak acids pass from the stomach into the bloodstream. Drugs that are weak bases pass from the intestines to the bloodstream. Drugs injected into muscle encounter more barriers than do drugs inhaled. Drugs inhaled into the lungs encounter few barriers en route to the brain. Drugs injected into the bloodstream encounter the fewest barrier to the brain but must be hydrophilic. Drugs contained in adhesive patches are absorbed through the skin.
