AN SC100 Lecture Notes - Lecture 6: Veterinary Laboratories Agency, Bone Meal, Epidemiology

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ANSC 100 Impact of Veterinarians and Animal Health Research
Nobel Prize Winners:
Carleton Gadjusek: 1976
Stanley B Prusiner: 1997
4 Veterinarians:
Dr. William Hadlow
oImpact: Kuru
Dr. Gerald Wells:
oImpact: Discovery of BSE
Dr. John Wilsemith
oImpact: BSE cause
Dr. Richard Marsh:
oImpact: BSE North America Regulations
Kuru:
Neurological disease that affected children and women (prion disease)
oMost common form of death for women
In Papau New Guinea
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Called “The Laughing Death”
1950’s: unknown disease of The Fore Tribe
Kuru Region: 65 km X 40 km
Disease onset: 5-60 years
Average clinical duration: 12 months
William Hadlow: (1921-2015)
DVM
USDA employee (United States Department of Agriculture)
Studying Scrapie in Berkshire, England
Visited a Kuru exhibit at a museum in London
oSuggested experimental transmission studies of Kuru to nonhuman primates
Carleton Gajdusek: (1923-2008)
Medical research in 1950’s
1st medical description of Kuru
Lived among the Fore
oHypothesized that cannibalism caused kuru (Fore tribe practiced cannibalism as a way of honoring the
dead)
oProved this hypothesis by animal transmission studies in 1960’s
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Document Summary

Dr. gerald wells: impact: discovery of bse. Dr. john wilsemith: impact: bse cause. Dr. richard marsh: impact: bse north america regulations. Neurological disease that affected children and women (prion disease: most common form of death for women. Usda employee (united states department of agriculture) Visited a kuru exhibit at a museum in london: suggested experimental transmission studies of kuru to nonhuman primates. Lived among the fore: hypothesized that cannibalism caused kuru (fore tribe practiced cannibalism as a way of honoring the dead, proved this hypothesis by animal transmission studies in 1960"s. Won the nobel prize in physiology or medicine in 1976. Economic impact on the canadian cattle industry ~ 7 billion dollars. Half of every cow and a third of every pig is not consumed. Rendering plants take death things and turn it into things we can use: meat and bone meal made from dead cows, fed to cows to increase growth.

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