BIOL107 Lecture Notes - Lecture 11: Centrosome, Tubulin, Microtubule

• School: University of Alberta
• Department: Biology (Biological Sciences)
• Course: BIOL107
• Professor: Cirelli,Damián

Document Summary

Eukaryotic cytoskeleton & cell movement: the cytoskeleton is composed of different classes of fibers and it forms a vast network throughout the cell, actin and microtubules are present in eukaryotic cytoskeleton. Prokaryotes (don"t rely on cytoskeleton to move things around) yes yes no no. The cross section shows that the radius is about 12nm: even in absence of centrosome, there"s still organs that can function as. Mtoc: microtubules serve as tracks for vesicle transport motor proteins attach to both the microtubules and a cargo to transport it along to a specific destination the proteins use the microtubules as tracks, motor proteins on the microtubules are polar. Kinesin moves toward the positive end (anterograde transport). Dynein moves toward the negative end (retrograde transport: they both walk on the tube (likely in a hand-over-hand fashion) Walk on the surface of the microtubule facing it.