BIOL107 Lecture 31: BIOL 107 – Lecture #31 – Genetic Expression – Pt.II

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BIOL107 Full Course Notes
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BIOL107 Full Course Notes
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Biol 107 lecture #31 genetic expression pt. ii: transcription. Dna is double stranded; rna is single stranded: therefore only one strand of the dna needs to be transcribed this is called the template stand, template strand. Runs 3" ---> 5" away from promoter. Rna polymerase recognizes and binds: sequence of dna that. Rna polymerase associates with to initiate transcription: dna is bound at promoter by transcription factors (tf) The promoter includes the transcription start side (+1) Rna polymerase binds to the double stranded dna at the promoter sequence that is at the 5" end of the non-template strand to be transcribed. Rna polymerase unwinds the double helix, to expose unpaired bases and identities the template strand. The template strand is read 3" ---> 5" from the promoter and the non-template strand is not read but is 5" --->3" from the promoter. Rna polymerase aligns the first 2 ribonucleotides, the 5" end from the new mrna molecule.

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