Biology 207 - Practice questions 2 - Answers
Question 1 The Online Mendelian
Inheritance in Man (OMIM) database
is a catalog of human genetics. As an
example of how it works try looking up
the two human Telomerase
components TERT (the protein) and
TERC (the RNA).
a) What do the abbreviations TERT
and TERC stand for?
TERT stands for Telomerase Reverse
Transcriptase and TERC stands for
Telomerase RNA Component.
b) What is the cytological locations of
TERT is at 5p15.33 (chromosome 5,
short arm, region 1, band 5, sub-band
33) while TERC is at 3q21-q28
(chromosome 3, long arm, region 2,
between bands 1 and 8).
c) Find these genes on the human
chromosome figure from the lecture 2
Note that individual genes are too
small to be seen on human
chromosomes. Each band contains
approximately 64 genes (32 000
genes / 500 bands). The location of
the TERT gene has been narrowly
defined but the location of the TERC
gene is just an estimate.
Question 2 Make a timeline showing the events of a typical cell cycle (G1, S, G2, mitosis,
cytokinesis) and add when Histones, Cohesins, and Condensins are added to DNA and when they
are removed. Question 3 A human cell is a / a . Make diagrams showing this gene and its chromosome in a
cell in (i) interphase, (ii) metap