b207p04.pdf

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Department
Biology (Biological Sciences)
Course
BIOL201
Professor
Michael Harrington
Semester
Fall

Description
Biology 207 - Practice questions 4 - Mutations Question 1 The A-gene makes a pre-mRNA with one intron. Make a diagram showing how the pre-mRNA is processed normally and what might happen if there is a mutation in the exon/intron boundary. Question 2 Recall that EMS causes GC-->AT bp substitutions. Consult a genetic codon table to answer this question. a) Can EMS cause nonsense mutations? Use a diagram to show why or why not. b) Can EMS revert nonsense mutations? Use a diagram to show why or why not. Question 3 The lacI gene in E.coli has mutational hot spots. Hot spots are sites in a gene that are much more mutable than other sites.
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