Lecture 11 - Apoptosis - Student - Filled In

Biology 201Dr Torah KachurLecture 11ApoptosisIntroduction We have been discussing how cells can divide and how that division can be controlledHowever the pathways controlling where and when a cell dies are critical to maintaining the health of an organismApoptosis or Programmed Cell Death is a major cellular pathway that is highly controlled by both intra and extracellular signals Objectives Define Apoptosis cytochrome c cell survival factors caspase Bcl2 apoptosome phagocytosisOutline three examples of when a cell would want to undergo apoptosisDescribe the cellular changes that occur once apoptosis is triggeredOutline two antiapoptotic signalsOutline three proapoptotic signals or conditionsExplain the function of a caspaseHow are caspases activatedOutline the function of the mitochondria in apoptosis what other function does the mitochondria haveDescribe 2 main targets of Bcl2How is Bcl2 activatedDescribe two possible ways that a cancer cell could avoid apoptosis Lecture Outline1 Purpose Page 591592 1