BIOL201 Lecture Notes - Lecture 11: Tradd, Tnf Receptor Superfamily, Caspase 8

392 views7 pages
Biology 201 Dr. Torah Kachur
1
Lecture 11 Apoptosis
Introduction
We have been discussing how cells can divide and how that division can be controlled. However, the
pathways controlling where and when a cell dies are critical to maintaining the health of an organism.
Apoptosis, or Programmed Cell Death, is a major cellular pathway that is highly controlled by both intra-
and extracellular signals.
Objectives:
Define: Apoptosis, cytochrome c, cell survival factors, caspase, Bcl-2, apoptosome,
phagocytosis,
Outline three examples of when a cell would want to undergo apoptosis
Describe the cellular changes that occur once apoptosis is triggered
Outline two anti-apoptotic signals
Outline three pro-apoptotic signals or conditions
Explain the function of a caspase
How are caspases activated?
Outline the function of the mitochondria in apoptosis, what other function does the
mitochondria have?
Describe 2 main targets of Bcl-2
How is Bcl-2 activated?
Describe two possible ways that a cancer cell could avoid apoptosis
Lecture Outline
1. Purpose (Page 591-592)
Unlock document

This preview shows pages 1-2 of the document.
Unlock all 7 pages and 3 million more documents.

Already have an account? Log in
Biology 201 Dr. Torah Kachur
2
2. Characteristics (Page 592, Figure 19-44)
Unlock document

This preview shows pages 1-2 of the document.
Unlock all 7 pages and 3 million more documents.

Already have an account? Log in

Get OneClass Notes+

Unlimited access to class notes and textbook notes.

YearlyBest Value
75% OFF
$8 USD/m
Monthly
$30 USD/m
You will be charged $96 USD upfront and auto renewed at the end of each cycle. You may cancel anytime under Payment Settings. For more information, see our Terms and Privacy.
Payments are encrypted using 256-bit SSL. Powered by Stripe.