IMIN405 Lecture Notes - Lecture 2: Zygote, Blastocyst, Cell Potency
Document Summary
Multilayer system that allows for the transformation of a single population of cells into others. Focus on bone marrow as the prototypical hematopoietic organ, other hematopoietic organs. Regulation of hematopoiesis (focus on csfs and transcription factors) How has this contributed to ethical issues associated. Considering the sites of hematopoiesis across development, illustrate how blood cell with stem cell research? production is a dynamic process. Early progenitor cell with the capacity to differentiate into a broad range of mature cells. Totipotent: the ability of stem cells to give rise to all embryonic and extra-embryonic tissues. E. g. the zygote that forms by the fusion of an egg and sperm. Pluripotent: the ability to give rise to all embryonic tissues, but not extra-embryonic tissues. E. g. stem cells in the inner cell mass of the blastocyst. Multipotent: the ability to give rise to the diverse cell types of one or a few tissues.