IMIN200 Lecture Notes - Adaptive Immune System, Innate Immune System, T Cell

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After studying lecture #4, you should be familiar with the following concepts: adaptive immunity. The adaptive immune response is an evolutionary newcomer that is restricted to non-cartilaginous jawed vertebrates. In contrast to innate immunity, adaptive immune responses are not restricted to specific classes of microbial molecules and adaptive immune receptors are not encoded within the germline. A further valuable feature of adaptive immune responses is that they improve or adapt upon repeated exposure to a given foreign toxin or microbe: antigens. Originally defined as antibody generating an antigen is now loosely defined as any molecule that simulates an immune response from b or t lymphocytes. Antigens are recognized directly by b cell receptors (bcr) on the surface of b cells. Alternatively, antigens are presented to t cell receptors (tcr) on the surface of t cells by antigen presenting. The bcr recognizes three-dimensional structures and mediates humoral responses to extracellular antigens.

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