MMI133 Lecture Notes - Lecture 11: B-Cell Receptor, Complement Membrane Attack Complex, Adaptive Immune System
2 Feb 2017
School
Department
Course
Professor
Document Summary
Everything that was a repeat from session 9. Difference between a transudate: watery interstitial fluid (not a lot of proteins) and an exudate: pus-like for infections have lots of proteins. Complement system importance and the most important by-products: Differences between acute: neutrophils and chronic: monocytes, macrophages infection. The adaptive or acquired system: specific generated host defenses. Innate immunity: non-specific defense: first line of defense against pathogens. Adaptive immunity: specific defense: specialized immune cells, specific response. Antigen: a foreign molecule that can be recognized by adaptive immune cells and elicit an immune response. The most immunogenic antigens are proteins: self/non-self recognition, memory generation, takes time to develop (~5-7 days, highly diverse and specific, generate memory, *mediated by: B lymphocytes: produce antibodies in response to specific antigens with the purpose of clearing infection, can also act as antigen presenting cells (apcs) in order to activate other immune cells to combat infection, maturation. Plasma b cells or memory b cells.
