MMI436 Lecture Notes - Lecture 2: Innate Lymphoid Cell, Lymphopoiesis, Cytotoxic T Cell

• School: University of Alberta
• Department: Medical Microbiology and Immunology
• Course: MMI436
• Professor: Paige Lacy

Document Summary

Adaptive immunity- more recently evolved, have antigen specificity and memory- more ample responses. Innate- responds very rapidly but does so without evidence of classical memory. Dendritic cells- lineage not so understood, call arise through differentiation of macrophages or from immature dc. Armed with igg antibodies can kill macroparasite worms by adhering to their surfaces move into tissues and make a lot of cytokines and chemokines. Basophils innate similar to mast cells very few in blood found in tick infections- very important in inhibiting their feeding. Don"t appear in peripheral blood as a mature cell only resident in tissues most histamine containing cells in body allergic reactions overlap with basophil. Lymphocytes: many subtypes and functions, in blood and tissue *adaptive and innate large nucleus relative to cytoplasm but then they start dividing and differentiate into different cells. Nk cells: innate in tissues and low number in circulation.