Lecture 6 Extra Notes.docx

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Department
Microbiology (Biological Sciences)
Course
MICRB316
Professor
Nicolas Vozza
Semester
Winter

Description
17nt melted, vound via the supercoiling the melting produced. But, the static nature of the diagram is misleading.  dsDNA is opening up  Model 1 a. RNA is twisted around DNA strand b. Lots of energy c. No know enzyme Model 2  Rotation causes strain: Supercoiling relaxed by gyrase and topoisomerase. + supercoils ahead.  – supercoils behind.  RNAP does not move. 1. initiation of replication AND 2. distribution of the duplicated template to daughter cells. Results discounted at first because
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