MICRB316 Lecture Notes - Lecture 19: Osmotic Pressure, Beta-Lactamase, Osmotic Concentration

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Lect: 16 changes made on notes on e-class check slide 16 and slide 14, 15 (reloaded notes) and lecture 18: slide 18. Srpr has homology to the repressor and it was tested: however, it did not bind to the dna so, it wasn"t the repressor srps was the repressor. srpr is an anti-repressor: binds srps. Changes: lect 18- clinical signiicance- amoxicillin, beta-lactam: and clavulanic acid (beta lactamase inhibitor)- bacteria have betalactamases induced when they encounter b-lactams clavulanic acid- used in combination with amoxicillin. Trimer of acrb subunits and tolc- make it look like a circle some crystal structure show that the trimmers are circular and the outer membrane. Tolc: barrel of gun also forms trimer circular tube which meets in the periplasm with acrb to form. Acra: cap, acrb: on membrane, and tolc: hangs from outer membrane from top. No more drugs can come in, drug is under some pressure.

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