MMI133 Lecture Notes - Lecture 20: Non-Gonococcal Urethritis, Pelvic Inflammatory Disease, Chlamydia Trachomatis

• School: University of Alberta
• Department: Medical Microbiology and Immunology
• Course: MMI133
• Professor: Judy Gnarpe

Document Summary

Define uti: asymptomatic vs symptomatic, common causes and definitions, differentiate b/w uncomplicated and complicated uti. Id the major cause of uti as e. coli. Summarize problems assoc with catheter use and biofilms. Majority of infections are acute and uncomplicated e. g. cystitis (bladder infection), urethritis. Most common type of nosocomial infection (especially associated with catheterization) Severe infections with complications affect kidney function (pyelonephritis) Valves control backwards flow of urine from bladder (storage) to ureters. Urine is normally low ph, has some antimicrobial properties and is normally sterile. A(cid:374)al(cid:455)sis of (cid:272)ell (cid:272)o(cid:374)te(cid:374)t, os(cid:373)olalit(cid:455), protei(cid:374) a(cid:374)d glu(cid:272)ose (cid:272)o(cid:374)te(cid:374)t, (cid:862)(cid:272)asts(cid:863) i(cid:373)porta(cid:374)t for diagnosis of complicated infection (urine sedimentation test) Hyaline cast (casts = (cid:862)molds(cid:863) that have found in urine) Lower uti = common symptom = want to urinate but cannot. Presence of significant numbers of bacteria (bacteriuria) in absence of symptoms. Can cause complications (scarring) in young children and in pregnant women.