MMI133 Lecture Notes - Lecture 15: Neonatal Conjunctivitis, Staphylococcus Epidermidis, Necrotizing Fasciitis

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Mmi 133 session 15 skin & eye infections. Skin = largest (cid:498)organ(cid:499) of the body, mucous membranes (cid:523)internal skin(cid:524: poor environment for microbial growth. Lysozyme, antimicrobial peptides: microbial inhabitants often g, washing reduces numbers but does not eliminate normal flora. Quickly re-establishes from hair follicles, sweat glands: all (cid:498)skin(cid:499) diseases do not necessarily originate from the outside, high moisture areas have larger microbial populations. Ie: respiratory infections, systemic infections environment: skin is a physical and chemical barrier to infection. Normal flora of the skin: both aerobic and some anaerobic bacteria grow on the skin. : anaerobes, live under the surface in follicales and glands. Mucous membranes: line body cavities (cid:523)(cid:498)body as a tube(cid:499)(cid:524, (cid:498))nternal skin(cid:499) cells secret mucus, sheets of epithelial cells attached to a basement membrane goblet, cilia, acidic ph, normal flora must like to live at lover phs. Respiratory tract: alpha streptococci, vaginal canal: lactobacillus *** Normal flora of the eye surface: normal flora of conjuctival surface:

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