MMI133 Lecture Notes - Lecture 31: Septic Shock, Viral Hemorrhagic Fever, Gram Staining
16 Jul 2018
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Bacteremia (just bacteria in the blood, does not have to be serious) Septicemia/sepsis - evidence of infection + systemic response (e. g. fever = pyrexia) Septic shock : caused by gram - and +, but is especially serious if caused by gram - bacteria due to release of lps (be called endotoxic shock ) Breach body"s first line of defence (e. g. trauma, burns) Infection and inflammation of tissues (e. g. perforation/penetration of intestine, appendicitis, invasion such as salmonella) Surgical procedures (e. g. oral surgery, rift in gums) Staphylococcus aureus and epidermidis (many vials may need to taken if needle pushes the flora into the blood sample) Found out through culture broth (if carbon dioxide is formed, bacteria is present), if carbon dioxide is detected, then a gram stain is done. Consequences of bacteremia: bacteremia clears spontaneously, bacteria carries and seeds into other areas of the body and causes focal infection, sepsis, septic shock. Macrophages and cytokines lead to shock and reduced oxygen exchange.
