NURS 106 Lecture Notes - Lecture 24: Iodised Salt, Thyroid Cartilage, Thyroid

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Consists of 2 lobes of endocrine tissue joined in the middle by narrow portion of gland-isthmus. Lumen filled with colloid (serving as extracellular storage site for thyroid hormone) Produces 2 iodine containing hormones, derived from amino acid tyrosine (t4 - thyroxine, t3) Forms the functional unit called a follicle. Still attached to tgb in the colloid until they are split off and secreted. Most t4 is activated to t3 outside the thyroid gland (by liver or target tissues) *the introduction of iodized salt has now decreased many goiter cases. Too much thyroid stimulating hormone, causing a large neck. Cross the membrane and act on the nuclei. Effect on metabolic action and heat production (calogeneric) Regulated negative feedback system between hypothalamic trh, anterior pituitary tsh and. Feedback loop maintains thyroid hormones relatively constantly thyroid gland t3 and t4. Secondary to a deficiency of trh, tsh or both (hypothalamus, although rare, and pituitary. Autoimmune function, requiring iodine replacement therapy.

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