NURS 116 Lecture 7: Immunity
25 Jan 2019
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Document Summary
Immunity: normal physiological response to microorganisms and proteins as well as conditions associated with an inadequate or excessive immune response. Optimal response - immune system that protects the body from the invasion of microorganisms, removes dead and damaged tissue/cells, and recognizes and removes cell mutations. Abnormal function - suppressed and exaggerated immune response. Not due to prior sensitization of an antigen. Natural killer cells, mast cell, eosinophils, basophils, phagocytic cells (macrophages, neutrophils and dendritic cells) Identifying and eliminating pathogens that might cause infection. Immune response intensifies after a second exposure due to memory b cells. Memory b cells are large b cells that have been exposed to an antigen and rapidly produce plasma cells (which secretes large amounts of antibodies) Antibody titer - relative amount of antibody in the serum. *leukocytes originates from either myeloid or lymphoid stem cells. Chemotaxis: chemical signals (n-formyl-methionine peptides, clotting system peptides, cytokines) that attract phagocytes through chemotactic factor induced pseudopod extension and retraction.
