NURS301 Lecture Notes - Lecture 5: Thioridazine, Thermoreceptor, Diplopia
16 Dec 2016
School
Department
Course
Professor
Document Summary
Genes that control cell growth and replication refer to 2nd diagram in carcinogenesis pdf. Tumor suppressor genes (tp53 in chromosome 17 activated in dna damage initiates apoptosis) Genes that control programmed cell death or apoptosis (eg. tp53) Genes that regulate repair of damaged dna. Neoplasia: abnormal (new) cell growth in: check points in the cell cycle (page # 53) cell proliferation cell differentiation. Proto-oncogene - these genes control how often a cell divides. A normal, nonmutant gene that codes for cellular growth. Oncogene (cellular oncogene) - are mutated forms of proto-oncogenes and the cell divides too quickly. In cancer - it is turned off so the cells grow out of control. Carcinogenesis: the process by which carcinogenic agents cause normal cells to become cancer cells, 3 types of cancers strongly run in family. Interaction between host and environmental factors colon cancer (both gender) Breast cancer (women: genetics and cancer prone families.
