NU FS305 Lecture Notes - Lecture 11: Hypernatremia, Extracellular Fluid, Fluid Compartments
21 Jun 2017
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Plasma compartment, then filtered by kidneys, same with electrolytes. About 60% of our body weight is water. Amount of (cid:449)ater i(cid:374) (cid:271)ody is depe(cid:374)da(cid:374)t o(cid:374) i(cid:374)di(cid:448)idual"s (cid:271)ody (cid:272)o(cid:373)positio(cid:374) Body fluids composed of water and electrolytes (ions dissolved in water) Composition of intra and extracellular fluids is different. Solvent for small molecules that participate in metabolic reactions. Water is important for allowing reactions between enzymes and substrates. Need to maintain bp and blood volume b/c we need to get oxygen to cells. Cardiac output = stroke volume x blood pressure. Water intake: fluids + food in diet, metabolic water (reactions that produce water) Thirst reflex indicates already dehydrated (if you"re already thirsty, it"s too late, you"re already dehydrated) Water loss: urine, sweat, breathing, feces, other minor losses. Electrolytes maintain fluid balance and are involved in acid-base balance. Anions = cations in body fluid compartments (always in balance) Osmosis: passive diffusion of water to region of high solutes (electrolytes, proteins, others)
