NU FS363 Lecture 11: Lecture 11 and 12 - Bacterial Infections

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Saliva: lysozyme (lysozyme breaks down peptidoglycan layer, more effective with gram. Organisms in your gut, colonizes, and causes illness. Food composition fat, carbohydrates (if your food is high in fat or carbs, it protects the organism as it transits through your stomach) Host defence (humans have defense mechanisms that protect us) Acidity (cid:894)orga(cid:374)is(cid:373)s do(cid:374)"t like ph i(cid:374) the sto(cid:373)a(cid:272)h(cid:895), pepsin, rate of flow (slow rate of flow. Stomach means they can adapt to the environment, but foods move through the body fast so it cannot adapt and it does(cid:374)"t like the ph/a(cid:272)idit(cid:455) either(cid:895) Normal microbiota (need this to help you digest nutrients and absorb things) When you disrupt your microbiota, you increase the risk of getting foodborne illnesses. When do you disrupt it? antibiotics, change in diet. Gut associated lymphoid tissue immune responses (largest immune system is your gut, affects whether an organism can cause you hard or not)

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