PMCOL305 Lecture Notes - Lecture 22: Timothy Leary, Ergotism, Ergot
24 Nov 2016
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Describe the typical dose and admin of lsd. Phantastica (some of the natural ones + traditional ones (ie lsd) Deliriants + anticholinergics = almost completely divorced from reality. Person remains in communication with present world + conscious (cid:271)ut (cid:449)orld is (cid:862)(cid:272)olored(cid:863) Little physiological toxicity, mostly psychological effects however, some of the new synthetic hallucinogens can be deadly. Da and noradrenaline have catechol backbones as do: Mandrake (plant used in witchcraft; ingredients that affect ach rs) Ergot: a fungus that infects rye contains lysergic acid and other complex ergot alkaloids. Some of the ergot alkaloids are potent vasoconstrictors and can cause uterine contractions. One is ergotamine, still used to treat migraines via vasoconstriction of cerebral bvs. In the middle ages in europe, outbreaks of ergotism from consuming infected grains. These complex ergot alkaloids bore high resemblance to lsd: severely constricted blood flow in limbs made the limbs feel like they were burning (cid:894) t.
