PEDS207 Lecture Notes - Liver Disease, Teratology, Prenatal Development

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Chapt 4 physical growth, maturation, and aging. Overview: body growth and aging, role of genes. Identify typical patterns of growth: distinguish between growth and maturation. Embryonic development conception to 8 weeks: differentiation of cells to form specific tissue and organs limbs formed at 4 weeks, human form noticeable at 8 weeks. Fetal development: 8 weeks to birth, continued growth by hyperplasia (cell number) and hypertrophy (cell size, cephalocaudal (head to toe) and proximodistal (near to far, plasticity (capability of taking on a new function). The cells have the ability to develop in one direction but can change their direction of development very quickly: at birth, the bodily system should be working independently. If the baby is born early, lots of time, the baby will have lung deficiency, jaundice (liver problems) Postnatal development: overall growth follows sigmoid (s-shaped) pattern, timing of spurts and steady periods can vary between individuals, timing differs between sexes.

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