PHYSL405 Lecture Notes - Lecture 12: Electroretinography, Retinal Pigment Epithelium, Stim
7 Nov 2016
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Current will be flowing (closed current) by putting electrode on skin and filament under the cornea (most sensitive organ in body) Do not want to alter optic pathway (need to maintain fine details) Erg = place something conductive (fine filaments) under the cornea = positive. Electrode (active) and little bit of exopholiant to minimize resistance. Erg: light-induced potential change that is related to light-induced electrical activity w/n retina. Vc vd = iar1 ib (r2+ r3 + r5 + r6) An electrical scheme of the resistances through which currents ia and ib flow when the retina is stim with light. The current source i, represents the electrical current generated in retina in response to a light stim. Current flowing (dark current) will be interrupted by light. Change of current across retina (only one directly modulated fast by light) current, causing a diminish in i diminish in erg. Closure of cgmp cation channel stops dark current when light is being transduced.
