PHYSL405 Lecture Notes - Lecture 5: Retina Horizontal Cell, Retina, Astrocyte

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Ri(cid:271)(cid:271)ons = sta(cid:272)ked (cid:449)ith (cid:448)esi(cid:272)les and allo(cid:449) us to (cid:862)re(cid:448) engine(cid:863) hard; stop dark current to stop the release of glutamate. Presynaptic ribbon = apposed to the invaginating axons of horizontal cells (yellow) and dendrites of rod bipolar cells (blue) Off cone bipolar cell dendrites form contacts at base (purple) 4 presynaptic ribbons are apposed to the invaginating dendrites of horizontal cells (yellow) and on cone bipolar cells (blue) Off cone bipolar cell dendrites form contacts at the cone pedicle base (purple) In rods = all or none (quantal); rods = sensitive but noisy = mistake possibilities. Post-synaptic r = only thing that differentiates on and off. Triad = 3 elements mingling with each other. In human retina 11 different bipolar cell types are revealed by golgi staining. More than 10 are for cones and a single type = for rods.

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