There is a time and place to be happy, you can"t be happy all of the time. In bipolar disorder, people have trouble regulating their happiness or their sadness. Manic episode: abnormal, persistent elevated mood, persistently increased goal-directed activity or energy for at least a week. There can also be decreased need for sleep, flight of ideas, distractibility, and more talkative. Stress can lead to both a manic episode and a depressive episode. Stress is shown to be related to the depressive episodes, just as it is in unipolar depression. Other types of stress, such as those related to striving or success may precipitate a manic episode. The cycle itself takes on a life of it"s own. Ssris pose some risk of suicide particularly in teenagers, and negative side effects are common. Anger is a motivating emotion, and if everyone was happy, then our motivations would decrease. Mixed reuptake inhibitors: blocks reuptake of norepinephrine and serotonin.