PSYCO258 Lecture Notes - Lecture 13: Donald O. Hebb, Synapse, Memory Consolidation

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Donald hebb (1948) proposed that learning and memory represented in the brain by physiological changes at the synapse. Long-term potentiation (ltp: enhanced firing of neurons after repeated stimulation, structural changes and enhanced responding. Muller and pilzecker (1900): found better performance on a memory test when a delay separated learning/testing. Consolidation transforms new memories from fragile state to more permanent one: synaptic consolidation occurs at synapses, happens rapidly, systems consolidation involves gradual reorganization of circuits in brain, happens slowly. Retrograde amnesia: loss of memory for events prior to trauma (taken as early evidence for standard model) Anterograde amnesia: loss of memory for events after trauma. Amnesia is often graded (memory for recent events is more fragile than for remote events) How sound can hack your memory while you sleep: march. What properties of the memory system make it both highly functional and also prone to.

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