ZOOL344 Lecture Notes - Lecture 7: Adaptive Immune System, Lipid Raft, Lipid Bilayer

• School: University of Alberta
• Department: Zoology (Biological Sciences)
• Course: ZOOL344
• Professor: John Chang

Document Summary

Plasma membrane phospholipid bilayer: lipid rafts are sphingolipid and cholesterol-rich membrane microdomains in the plasma membrane, sphingolipids have long, saturated acyl chains that allow them to pack tightly in the bilayer forming a gel phase. Outside of these microdomains the bilayer is fluid-like: phospholipids are not distributed randomly, rafts have been shown to selectively include some proteins and exclude others. Thus, providing a mechanism for the lateral sorting of specific proteins in the membrane: lipid rafts are involved in the activation of b cells when the adaptive immune response comes into play. These are highly specific to the pathogen and usually rely on the production of specific antibodies. Innate responses serve as a primary barrier that calls into play the adaptive response. They work together to protect an organism over the short term and the long term: you still need to have both to have an effective immune system, b lymphocytes: immune response, adaptive immune responses are carried out by.