KNES 260 Lecture 20: 03/03/17

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Includes follicles/follicular cells and areolar connective tissue. Can also be referred to as thyroxine, th, t3, or t4. Last two are based on # of iodines attached to the hormone. Synthesis requires iodine which is added in the colloid space. Side effects are increased breathing, increased heart rate, and higher uptake of sugar in gi tract. Released if blood ca2+ is too high. Increased bones absorption of ca2+ (largest effect) Causes include tumor on thyroid gland or grave"s disease (an auto-immune disease) Symptoms are tachycardia, nervousness, hyperactivity, weight loss/hunger, heat, exophthalmos (bulging eyes) Causes can be autoimmune, low tsh, or low iodine. Autoimmune turns off the thyroid in this case, as opposed to grave"s disease which turns it on. Symptoms: cold and lethargic, weight gain, brittle hair and nails, mental sluggishness. Caused by low th in first 2 years of life. Effects: severe mental impairment, low muscle tone, sleepiness. Enlargement of thyroid caused by either hyper- or hypothyroidism.

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