PSYC 375 Lecture Notes - Lecture 14: Cannabinoid, Gaba Receptor, Ligand-Gated Ion Channel

• School: University of Calgary
• Department: Psychology
• Course: PSYC 375
• Professor: Simon Spanswick

Document Summary

Type 1 synapse- excitatory, typically located on the dendrites. Type 2 synapse- inhibitory, typically located on the cell body. The effects of neurotransmitters on ionotropic channels are typically very quick and simple. They change the ion flow and thus, the membrane voltage. Autoreceptors- respond to the neurotransmitter released by the neuron. The chemical must be synthesized in the neuron or otherwise present in it. When the neuron is active, the chemical must be released and produce a response in some target. The same response must be obtained when the chemical is experimentally placed on the target. A mechanism must exist for removing the chemical from its site of activation. Small-molecule transmitters- quick acting, often synthesized from dietary nutrition. Choline comes from the breakdown of fats in the diet. The reverse action takes place in the synapse. Choline and acetate are taken back up into the presynaptic neuron and can be reused.