ANSC 3080 Lecture Notes - Lecture 13: Hypothalamus, Sertoli Cell, Vas Deferens
27 Mar 2018
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Document Summary
Sex is needed for 2 individuals to produce germ cells which fuse to produce an offspring. Difference (sexual dimorphism) carried by genes = sex chromosomes (mammals: xx=f, During early fetal life, gonads are undifferentiated. Extra-embryonic origin (outside of the embryo mass) Pgcs colonize the genital ridge (gonadal ridge) to form indifferent gonads. Differentiation of cortex into ovary or medulla into testis. Testis organization through transient expression of genes (testis differentiation factor tdf) from the sry (sex-determining region y) gene right beside the wolffian duct. Wolffian duct is located in the embryonic kidney, mullerian duct is not in the kidney but. Usually give a name that include (factor) when we have not characterized a substance yet. The default is female when there is no tdf. Rete tubules = formed from the deep part of the sex cords. Mesonephric tubules (future efferent ducts) connects to the rete tubules. Undifferentiated sec cords form testicular cords with pgcs.
