ANSC 3270 Lecture Notes - Lecture 18: Attention Deficit Hyperactivity Disorder, Basal Ganglia, Nucleus Accumbens

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The pfc, basal ganglia and reduced behavioural flexibility. Appraisal, supervision, planning, moderating impulsivity and distractibility (preference for small rewards over delayed bigger rewards) Impaired function contribute into ocd and drug addiction (abnormal lock into goals) and. Add (attention deficit disorder, abnormal failures to achieve goals) E. g. if there is pfc lesion = dog shuffle between 2 bowls of food, knock automatically for a door that says please knock. Connect decision-making region of cortex with motor cortex. Loops from processing region of the cortex to action. Turning stimulus into response, intention into action. Initiate behaviour in response to unlearned innate triggers, learned cues, motivational state. Loops run from and to the cortex. From info processing regions of cortex basal ganglia either direct (activational) or indirect pathway (inhibitory) thalamus behaviour-generating region of cortex. All parallel loops are inhibited by pfc action. Form 1: abnormal repetitive behaviours (arbs) in spontaneous repertoire. Form 2: poor flexibility in tasks that require behaviour change.

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