ANSC 4100 Lecture Notes - Lecture 13: Behavioral Enrichment, Homeostasis, Corticosteroid
11 Apr 2018
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Lecture #13 environment and animal health: research animal welfare and disease welfare/animal health holistic view of total well-being (biological, physiological, psychological, social) refinement minimize adverse stress that animals experience. Focus on factors preventing disease and abnormal states. Welfare is compromised when physiologic health and/or psychological well being are negatively affected. To carefully document conditions scientific integrity, validity, repeatability and quality control are required. Other important factors determining health status and disease susceptibility intrinsic factors (age, sex, strain) chemicals: water, diet, environmental enrichment, pathogens in the environment social groupings. Environment how does it increase susceptibility to disease: homeostasis, perceived stressor shifts balance activation hpa axis if persists, changes to basal metabolism may occur. The nervous, endocrine and immune system are all interconnected via. chemical signals from messengers (peptides, hormones, neurotransmitters, cytokines) Interactions between host, agent and environment some conditions sufficient on own to induce disease: disease triangle = alignment of various factors between host, environment and agents.
