BIOC 2580 Lecture Notes - Lecture 1: Micelle, Amphiphile, Sodium Hydroxide

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Lecture 1 lipids: fatty acids, triglycerides, and phospholipids. Biological lipids are a structurally diverse group of molecules. Defined by their common chemical property: hydrophobicity: they are the most hydrophobic of all macromolecules. Lipids are the biomolecules that will partition into the organic solvent phase (so, we use organic solvents to dissolve lipids) Typically the solvent used is a 2:1 mixture of choloform and methanol. Lipids are diverse with both their structure and function. Triacyglycerols (fats and oils): energy storage biggest store of energy. Phospholipids and sterols: structural elements of biological membranes. Steroid hormones, paracrine hormones (prostaglandins, diacylglycerols): signal transduction cell to cell communication. Vitamins a,d,e,k: vitamin a and d (hormone precursors, vitamin e (antioxidant, vitamin k (blood clotting) Carotene: light-absorbing pigments colour of tomatoes, carrots, pumpkins, some birds. Lipids can often occur covalently linked to other classes of biomolecules. Lipoproteins: vldl, hdl, ldl = plasma lipoproteins associated with cardiovascular health and disease: proteins covalently linked to lipids.

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