BIOL 1080 Lecture Notes - Lecture 23: Calorie Restriction, Sarcopenia, Maximum Life Span
5 Apr 2016
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Document Summary
More on biological theory of aging 3: the rate of living theory. The normal wear and tear" of life, compounded by abuses to the system, results in an accumulaion of damage that is irreplaceable. Most of this topic (rate of living theory) has grown around the observaion of caloric restricion and what happens to the body when large amounts vs small amounts of food are consumed. Caloric restricion may opimize health span, at the risk of decreased ferility. Assumpion is that the person moves to a more nutrient dense diet and only the calories are restricted. Evoluion is driven by an increase in ferility with increase in caloric intake and decreased if the mother themselves are malnourished. Maximum lifespan occurs at a certain extent of slight starvaion (30% less than normal caloric intake) When caloric intake exceeds normal (as it oten does today) both lifespan and reproducive curves decrease signiicantly.
