BIOL 1080 Lecture Notes - Lecture 22: Senescence, Sarcopenia, Genetic Variation

84 views2 pages

Document Summary

Theory 1: use it or lose is we use less mental and physical abilities as we age, and therefore lose these abilities over time. Alzheimer"s risk increases as we age; time from onset memory impairment to death vs. Years of schooling, cognitive activieties (i. e. reading, crossworkds, puzzles), cognitive traing and physical activity reduces dementia. Physical activity must be greater than 3x per week reduced alzheimer"s. Protection does not appear due to less brain damage with agin, rather it seems to be improving copying mechanism. Sarcopenia: decrease in muscle mass and muscle quality, it decreases metabolic reserve and causes weakness, disability, mobility, mortality. Theory 2: its in our genes genetic variation in longevity genes may influence lifespan. Using model systems, like yeast, fruit flies, c. elegans (worms) and rodents: knock out or add specific genes to order to examine functionality. Genetic variation in humans can be examined by genotyping: centurians vs. young/old subjects, longitudinal studies (follow cohort subject over time)

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions