BIOL 1090 Lecture Notes - Lecture 2: Centrosome, S Phase, Endoplasmic Reticulum

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Organelles and cytoplasm divided more or less equally between daughter cells, not necessarily exactly equal. But dna has to be duplicated exactly and equally between daughter cells. Interphase: most time spent in g1 phase (adjusting from the last division) (gap 1 phase) Over half the time spent here: if it crosses into s phase, it is committed to replication. Must then complete another round of cell division. Dna replication: second gap phase (g2 phase) More resting and making sure everything is duplicated properly. Total takes about 24 hours for human cells. Cells can exit the cell division cycle to be in a state called g0 in which they are not dividing: called quiescent. Centrosomes organize the microtubules by their polarity, having all positive ends shooting in the same direction (fig 14. 18) Each sister chromatid is itself a complete chromosome, but the pair of sister chromatids is also referred to as a complete chromosome.

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