BIOL 1090 Lecture Notes - Lecture 8: Integral Membrane Protein, Lipid Bilayer, Lipid Raft

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All membranes share common properties: ~ 6 nm thick, stable, flexible, self-assembly: small lipid blobs come together to form one big blob; end liposome has the characteristics of both original liposomes. Influx: materials being brought into the cell: efflux: materials being brought out of the cell, net flux: net movement of material. Movement of substances across cell membranes: lipid bilayers do not allow many compounds to pass through them freely: small, uncharged molecules cross membranes relatively easily (ex. O2, co2, no) large/ polar/ charged compounds cannot easily cross lipid bilayer: specific mechanisms exist for the controlled transport of many substances across membranes. Simple diffusion: very small molecules, uncharged, down a concentration gradient, solvent is what moves it moves around the solute. Aqueous pore: water substance can now move through. Gated: can be open (under certain situations ex. change in voltage / energy potential) or closed: number of proteins associated with pore-influence of gated channels.

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