BIOL 1090 Lecture Notes - Lecture 9: Oxidative Phosphorylation, Phospholipid, Atp Synthase

• School: University of Guelph
• Department: Biology
• Course: BIOL 1090
• Professor: Andrew Bendall

Document Summary

Mitochondria: usually depicted as oval, double membrane organelles, mitochondria undergo rounds of fusion and fission and their shape can change to be considered tubular, mitochondria undergo frequent fusion and fission, have two membranes. Outer mitochondrial membrane (omm: high lipid, low protein, contains many enzymes with diverse metabolic functions. Porins: large channel proteins that when open, membrane is freely permeable: inner mitochondrial membrane (imm) Double-layered folds = cristae: cristae: increase membrane surface area and contain machinery for aerobic respiration and atp formation. Rich in a phospholipid called cardiolipin (characteristic of bacterial membranes) *nucleoid imm associated but not membrane bound (mitochondrial dna) Major function of mitochondrion: provide cells with energy (atp) obtained from glucose. Oxidative phosphorylation: atp synthesis in the mitochondria: step 1: electron transport and proton pumping (generates an electrochemical gradient, step 2: proton movement down electrochemical gradient powers atp synthesis. **when atp formation is driven by energy released from electrons removed during substrate oxidation, the process is called oxidative phosphorylation.