BIOL 1090 Lecture Notes - Lecture 1: Deoxycytidine Monophosphate, Deoxyguanosine, Nucleic Acid Double Helix
Document Summary
Evolutionary function mutation: genotypic function replication. Based on the separation of the parental dna strands, synthesis of new complementary strand. Replication passes different genes and traits from generations before from both parents: phenotypic function gene expression. Determined by genetic makeup and environmental influences: evolutionary function mutation. Population variation is the substrate on which natural selection acts. Purine and pyrimidine nucleotides in polynucleotide chains are connected by phosphodiester bonds: Dna is double-stranded and the strands are anti-parallel. Opposing strands are aid to be complementary. Most common form of dna is called b-dna. Strands are held together by hydrogen bonds between bases on opposing sides interactions between adjacent stacked bases and hydrophobic. Eukaryotic chromosomes are composed of proteins, dna and rna: first level of condensation packaging dna as a negative supercoil into nucleosomes. Dna is wrapped around a nucleosome core of 8 histone proteins and anchored by a 9th.
