BIOL 3010 Lecture Notes - Myostatin, Myogenesis, Sonic Hedgehog

12 views4 pages
Published on 29 Jan 2013
Department
Course
Professor
Muscle
MUSCLE TYPES
Skeletal – syncitial
differential splicing different muscle fiber isoforms
Cardiac – mechanical coupling (intercalated disks)
Smooth – not syncitial, not striated; random actin-myosin arr.
MYOEPITHELIAL – iris dilator, mammary, salivary, sweat
glands; important for secretion
**from ectoderm associated w/ above organs**
DESCRIPTIVE EMBRYOLOGY
Mesoderm is initially a bilayer
PARAXIAL mesoderm axial skeleton
skeletal muscle
dermis
initially forms SOMITOMERE “whorls”
somitomeres (mesenchymal) SOMITES (epithelial)
first 7 remain somitomeres and form face/throat musc.
37 total somite pairs form in humans
ventral, LATERAL PLATE mesoderm splanchnopleuric
cardiac/smooth muscle
(dorsal, lateral plate somatopleuric mesoderm)
SOMITE DIFFERENTIATION – occurs anterior to posterior
ventral – SCLEROTOME axial skeleton, skull
medial – MYOTOME myogenic cells
1. ventral hypomere (lateral/ventral
body wall musculature)
2. dorsal epimere (spine muscles)
dorsal – DERMOTOME dermis
paraxial mesoderm
somitomere
somites
lateral plate
sclerotome
myotome, myogenic
dermotome
Unlock document

This preview shows page 1 of the document.
Unlock all 4 pages and 3 million more documents.

Already have an account? Log in

Get OneClass Notes+

Unlimited access to class notes and textbook notes.

YearlyBest Value
75% OFF
$8 USD/m
Monthly
$30 USD/m
You will be charged $96 USD upfront and auto renewed at the end of each cycle. You may cancel anytime under Payment Settings. For more information, see our Terms and Privacy.
Payments are encrypted using 256-bit SSL. Powered by Stripe.