BIOM 2000 Lecture Notes - Lecture 3: Myofibril, Sarcomere, Motor Neuron

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Muscles made of thin elongated cells held together by connective tissue: respond to stimuli by contracting. Attached to bones & undergo fusion with several nuclei. Contraction speed is based on skeletal muscle fibres. Muscle fibre enclosed by endomysium fibres are wrapped in perimysium to for fascicles epimysium surrounds fascicles. Form muscle tissue in hollow organs (blood vessels or gastrointestinal tract) Involuntary & controlled by automatic n. s & hormones. Muscle is made of cardiomyocytes (cardio =<3, myo= muscle, cyte= cell) @ wall of <3. Muscle fibres are separated by connective tissue (endomysium) Muscle cell sub units = myofibril: made of 2 filaments: myosin (thick) & actin (thin) Space between the two ^ is called a sarcomere. Muscles need to be stimulated to contract (nerve cell) 2 motor units: motor neuron & skeletal muscles stimulated by that neuron neuromuscular junction contracts b/w motor unit & muscle fibre.

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