BIOM 3200 Lecture Notes - Lecture 8: Voltage-Gated Potassium Channel, Neurotransmission, Microglia

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Homeostasis: a term coined in the early 20th century by the american physiologist, walter. Cannon, to describe the relative constancy of the chemical composition of the blood, despite considerable variations in external conditions. Distinction of internal and external environments was proposed by french physiologist, The relative constancy of the internal environment (blood, extracellular fluids) allows the levels of cellular metabolism to be tightly regulated, within optimal ranges. Lungs, kidneys, digestive tract, and cardiovascular system are all organs/systems that are essential for maintaining the constancy of the internal environment. In homeostasis, all systems are able to play their particular roles by integrating with other systems. Temperature regulation, water and electrolyte regulation, nutrient regulation, excretory product regulation, ph regulation, oxygen and co2 regulation, etc. all involve the activities of multiple systems that interact in an integrated manner. Two systems are primarily involved in this regulatory process: nervous system and the endocrine system.

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